Monte-Carlo optimization of beam properties and dose conformation of small field intensity modulated protontherapy for beyond state of the art eye treatment

Eustache Gnacadja

The project consists in two different parts. The first goal is to build a numerical model of the Ion Beam Applications (IBA) passive scattering eye treatment beamline (so-called the eyeline) to allow the development of an in-simulation calibration workflow. Such workflow will then support and accelerate the already existing experimental commissioning procedure of the system.

The second part of the project aims to propose a design of the IBA ProteusOne (P1) system to allow eye tumors treatment. The IBA P1 system is a modern proton therapy facility made of a SuperConducting SynchroCyclotron (the S2C2) which delivers a proton beam at the nominal energy of 230 MeV, an energy degrading wheel, and a 270° rotating compact gantry. The proposed design must fulfill the same clinical requirements as the already existing eye treatment proton therapy systems, such as the IBA eyeline. Those requirements are imposed on the dosimetric properties of the dose deposition profiles, namely the distal fall-off, the lateral penumbra, the transverse and in-depth flatness, and the dose rate of the system. The main modifications that will be made on the system consist in positioning range shifting and beam collimating devices inside of the nozzle (after the last bending magnet).